沙眼衣原体和解脲支原体感染与不孕

Experimental study of relationship between sterility and infections of chlamydia trachomatis and ureaplasma urealyticum

目的探讨沙眼衣原体（ＣＴ）、解脲支原体（ＵＵ）的生殖道感染与不孕关系。方法采用聚合酶链反应技术（ＰＣＲ）检测沙眼衣原体和解脲支原体的ＤＮＡ。结果不孕组８８例中，ＣＴ阳性率２５０％，ＵＵ阳性率６２５％，对照组１４１例中，ＣＴ阳性率１１３４％，ＵＵ阳性率２８４％，ＣＴ和ＵＵ的χ２值分别为７０３和２６０１，Ｐ＜００１，有显著性差异。结论沙眼衣原体和解脲体支原体的生殖道感染是不孕的重要因素之一。

Objective To explore the relationship between sterility and genital tract infection due to chlamydia trachomatis(CT) and ureaplasma urealyticv (UU).Methods DNA of CT and UU was detected with polymerase chain reaction(PCR) technique.Results The positive rate of CT DNA and UU DNA in the group of 88 sterility cases was 25 0% and 62 5% respectively,while in the control group of 141 cases,the positive rate of CT DNA and UU DNA was 11 34% and 28 4%,and the χ 2 value of CT and UU was 7 03 and 26 01 respectively(P<0 01).The difference was significant.Conclusion Genital tract infection of CT and UU is one of the important factors inducing sterility.