进展期胃癌术后化疗远期疗效的临床探讨

Clinical Study on the effect of Chemical Therapy to Stomach Cancer after Operation

我院1980年～1986年收治81例进展期胃癌术后病人，随机分治疗组41例，对照组40例，治疗组病人用MF方案，对照组病人非计划性单用FT—207或UFT及中药治疗。结果：治疗组五年生存率14．63％，对照组五年生存率5％，两组差异显著（P<0．01），MF方案给药时间短，毒副作用小，且两年内按化疗程序地有规律治疗，疗效显著。

This paper comparatively analyses the effect of chemical therapy to 81 cases onstomach cancer after operation, which are all at the developing stage from 1980 to 1986in our hospital. And all the cases are divided into two comparative groups stochastically. One group has 41 cases treated by MF while the other group has 40 cases only by FT-207 at intervals or VFT plus Chinese traditional medicine irregularly. The results ofthe two groups are distinctly different (P<0. 01). The survival rate in 5 years of thefirst group is 14. 63 %,and the survival rate of the second is 5%. The MF therapy is verified in the clinical application that the effect of controlling the cancer into stability isvery distinct on a short-period-treatment basis with minimal side effect as long as thepatients receive the regular chemical treatment of consolidation according to the correctprocedures within two years.