120例癫痫患者的甲襞微循环观察

The Observation on Nailfold Microcirculation in 120 Cases with Epilepsy

目的：为探索癫痫的发病过程与外周微循环改变的关系以便配合治疗。方法：观察238名正常人与80例癫痫间歇期、40例发作期患者甲襞微循环血管形态、流态和襻周状态十三项指标的异常串。结果：间歇期患者十三项指标中有九项异常率明显高于正常人（P＜0．01），发作期患者有十三项指标异常率明显高于间歇期（P＜0．01）。结论：癫痫患者的外周微循环改变是一种病理现象，其发生机理与神经一体液调节障碍有关。改善微循环障碍状态有助于患者的康复。

Purpose:To explore the relations between the course of epileptic attack and the changes of the peripheral microcirculation so as to coordinate the treatment.Methods:The forms of the microcirculatory vessels in the nail fold were observed in 238 healthy people,80 cases in epileptic intermission and 40 cases in epileptic attack. The unusual rates of 13 indexes in fluid state and the state surrounding capillary loops were examined with X2.Results: 9 unusual rates out of 13 indexes in tbe intermttent epileptic patients are apparently higher than those of the healthy people(P<0.01) and the 13 unusual index rates in patients in epileptic attack are higher than those in the patients in epileptic intermission(P<0. 01).Conclusion:The changes in the peripheral microcirculation of epileptics are pathological phenomena and its mechanism is associated with the obstruction of nerve-body fluid regulation. It is conducive to the patient's rehabilitaton to improve tbe obsmiction of mcrocirculation.