摘要
目的:观察不同浓度的罗哌卡因硬膜外麻醉在肛门直肠部手术的临床效果。方法:选择90例ASAⅠ~Ⅱ级肛门直肠手术患者,随机分为3组,分别给予浓度为I%(A组),0.5%(B组),0.375%(C组)的罗哌卡因。分别于术中比较3组镇痛效果、运动阻滞程度、尿潴留、血压下降等项目。结果:3组镇痛效果均满意,视觉模拟评分(VAS)差异无显著意义,但C组运动阻滞程度、尿潴留、血压下降显著低于A组(P〈0.05)。结论:下肢无力、尿潴留、血压下降C组明显少于A组,有显著性差异(P〈0.05),说明0.375%罗哌卡因低位硬膜外麻醉应用于肛门直肠部手术镇痛效果良好,下肢无力、尿潴留、血压下降发生率低,是用于肛门直肠部手术麻醉的适宜浓度。
Objective: To observe the effects of various concentrations of ropivacaine in epidural anesthesia during anorectal operation. Methods: Ninety patients with ASA Ⅰ~Ⅱ performed anorectal operation were randomly divided into 3 groups. They were anesthetized with 1% (A) , 0.5% (B) and 0. 375% (C) ropivaeaine solution, respectively. During operation, the analgesic effect, motor block level, urine retention, blood pressure, and other indicators were observed in all patients. Results: Satisfactory analgesic effects were observed in 3 groups. The visual analog score (VAS) was not different in 3 groups, but the motor block level, urine retention, blood pressure was significantly lower in group C than in group A(P 〈 0.05). Conclusion: Ropivacaine at 0. 375% is a suitable concentration in epidural anesthesia during anorectal operation. This concentration has shown a satisfactory analgesic effect, and lower incidence of limb weakness, urinary retention and blood pressure lowing during the operation.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2009年第15期1408-1409,1423,共3页
Chinese Journal of New Drugs