脑梗塞患者血浆白介素6、8的观察

Plasma interleukin-6 and 8 in patients with cerebral infarction

为了研究脑梗塞后白介素６、８的变化及其意义，用双抗体夹心ＥＬＩＳＡ法对５５例脑梗塞患者血浆ＩＬ－６、８进行了检测。结果发现，急性期ＩＬ－８阳性率无增加，恢复期ＩＬ－８阳性率及含量明显增加。急性期和恢复期ＩＬ－６阳性率均有增加趋势，提示ＩＬ－６的变化较ＩＬ－８早，与脑缺血过程可能有关。

Purpose:To determine the change of plasma IL-8,IL-6 in patients with cerebral infarction. Method :ELISA was applied to determine plasma IL-6 and IL-8 in 55 cases. Result:The positive rate of IL-8 did not increase in the patients at acute stage (P>0.05), and was markedly higher at the convalescent stage than that in the control (P<0.05).IL-6 positive rate was higher in both acute and convalescent stage than that in the control. Conclusion:The change of IL-8 was the result of infection after cerebral infarction, and IL-6 may play a little role in cerebral ischemia.