双氯芬酸钠滴眼液控制准分子激光角膜切削术后眼痛

Topical diclofenac sodium in reducing ocular pain after Photorefractive Keratectomy

本研究将病人随机分为３组，每组各３０人（６０眼），通过对照组及不同的用药来观察双氯芬酸钠控制准分子激光角膜切削术后的眼部疼痛的有效性和安全性。结果表明：角膜伤口的愈合时间，对照组、药物Ⅰ组和Ⅱ组分别为３．５７±０．９１天、３．９３±１．３０天和３．５７±１．０５天，无显著性差异（Ｐ＞０．０５）；术后３月的屈光度分别为０．０９±１．０６Ｄ、－０．２９±０．９６Ｄ和－０．２１±１．０９Ｄ，无显著性差异（Ｐ＞０．０５）；术后３月的角膜混浊分别为０．２５±０．４７级、０．３１±０．５４级和０．２５±０．５１级，无显著性差异（Ｐ＞０．０５）；用药组病人对疼痛控制满意。

This study is designed to evaluate the efficacy and safety of topical diclofenac in reducing ocular pain after Photorefractive Keratectomy(PRK).We performed a randomized observation,parallel group,diclofenac group Ⅰ and diclofenac group Ⅱ is 30 patients(60 eyes),respectively.The corneal healing time is 357±091 days,393±130 days and 357±105 days,respectively(P>005);At 3month,refrection is 009±106D,-029±096D and -021±109D(P>005);corneal haze is 025±047 grade,031±054 grade and 025±051 grade(P>005);Diclofennactreated patients are satisfied with the results of topical diclofenac in reducing ocular pain after PRK.Topical diclofenac in reducing ocular pain after PRK is effective and safe.