摘要
目的:探讨18F-FDG PET/CT在头颈部肿瘤的临床应用价值。方法:58例头颈部恶性肿瘤病例,男37例,女21例,年龄21~78岁。其中:牙龈癌3例,上颌窦癌2例,舌癌2例,腮腺癌1例,鼻咽癌24例,喉癌8例,甲状腺癌4例,原发灶不明的颈部淋巴结转移瘤14例。使用18F-FDG行全身PET/CT扫描,依据PET图像、CT图像和PET/CT融合图像及标准化摄取值(SUV)进行综合评价。结果:29例放疗患者中的11例拟行根治性放疗的患者,有4例改行姑息性放疗,8例重新勾画了放疗靶区及调整了放疗剂量,3例改行其它治疗;15例进行了放疗后的疗效评估;14例原发灶不明的颈部淋巴结转移瘤8例找到了原发灶。结论:PET/CT可以对头颈部恶性肿瘤进行准确的临床分期,精确勾画放疗的生物靶区,准确而快捷地确定肿瘤复发的位置与侵犯范围,在颈部不明原发灶转移瘤的应用中具有简便、快捷、无创和灵敏等临床特点。
Objective： To investigate the clinical application of 18F-FDT PET/CT in head and neck neoplasms.Methods： Fifty-eight cases with malignant head and neck neoplasms were studied,37 males and 21 females,aged from 21 to 78;out of the 58 cases,there were 3 cases of gingival carcinoma,2 cases of maxillary sinus carcinoma,2 cases of tongue carcinoma,1 case of parotid carcinoma,24 cases of nasopharyngeal carcinoma,8 cases of laryngeal carcinoma,4 cases of thyroid carcinoma and 14 cases of cervical lymph node metastatic carcinoma.18F-FDG PET/CT whole body scans were performed,and comprehensive evaluation was made based on PET image,CT image,PET/CT fusion images and standard uptake volume（SUV）.Results： Out of the 29 patients undergoing radiotherapy,11 cases intended to receive radical radiotherapy,while 4 out of them changed to palliative irradiation.Target field of radiotherapy of 8 cases was re-located and the dosage was adjusted,and 3 cases changed to receive other treatment;curative effect evaluation after radiotherapy was made to 15 cases;primary lesions were searched out in 8 cases out of the 14 cases with cervical lymph node metastatic carcinoma.Conclusion： PET/CT can make accurate clinical stage of malignant head and neck neoplasms,accurately locate biological target volume of radiotherapy and quickly decide the location of carcinoma reoccurrence.It is of clinical application value with the advantages of simple and fast operation,non-invasion and sensitiveness in neck metastatic carcinoma with unknown lesion.
出处
《华西医学》
CAS
2009年第6期1490-1492,共3页
West China Medical Journal
