新生儿高未结合胆红素血症340例临床病因分析及治疗

Neonatal Unconjugated Hyperbilirubinemia Clinical Causes of 160 Cases of Analysis and Treatment

目的:探讨新生儿高未结合胆红素血症病因构成、发生规律及防治。方法:对340例新生儿高未结合胆红素血症进行病因综合分析。结果:(1)病因以感染因素占首位,其次是溶血因素及围产因素;(2)病因与发病时间的关系:溶血因素及围产因素均发生在日龄<3 d内,发病日龄>3 d以感染因素为主,还有母乳性黄疸。结论:早期新生儿高未结合胆红素血症以溶血因素及围产因素为主,中晚期新生儿高未结合胆红素血症则以感染因素为主。故加强围生期保健,加强预防及抗感染,减少孕期及产时并发症的发生可有效减少新生儿黄疸的发生。

Objective： To evaluate neonatal causes of unconjugated hyperbilirubinemia composition, Occurrence and Control. Methods： Three hundreds and forty cases of neonatal unconjugated hyperbilirubinemia conducted a comprehensive analysis of the cause. Results： （1） factors that accounted for the cause of infection in the first place, followed by the hemolytic factors and perinatal factors; （2） Etiology and pathogenesis of time： hemolytic factors and perinatal factors have occurred in the age（3d, the incidence of age）3d the main factors for infection, as well as breast milk jaundice. Conclusion： The early neonatal unconjugated hyperbilirubinemia with hemolytic factors and perinatal factors mainly in the late neonatal unconjugated hyperbilirubinemia are the main factors of infection. Therefore, to enhance perinatal care. Strengthen prevention and anti-infection, to reduce production when the complications of pregnancy and can be effective in reducing the incidence of the occurrence of neonatal jaundice.