复方甲硝唑栓的含量测定

DETERMINATION OF METRONIDAZOLE IN SUPPOSITORY

应用吸光度线性方程组分光光度法，不经分离直接测定复方甲硝唑栓中甲硝唑和氯霉素含量，测定波长为278.0nm和320.0nm，平均回收率甲硝唑为100.05％，（RSD-0.17％），氯霉素为100.16％（RSD=0.47％）。方法不受栓剂基质的干扰，定量准确、简便、快速，适宜于医院制剂分析。

In this paper, Metronidazole suppository was analyzed directly without any separation by using absorbance linear-equation spectrophotometry. The average recoveries of Metronidazole and Chlormphenicol were 100. 05 % (RSD=0.17 % ) and 100. 16% (RSD= 0.47% ) respectively. The method was accurate, simple and rapid.