准确预测人脑肿瘤变异的首例无创技术

First Noninvasive Technique To Accurately Predict Mutations In Human Brain Tumors

宾夕法尼亚大学医学院神经外科副教授Donald O’Rourke博士表示，“肿瘤领域的研究目前已进展到了确定导致肿瘤发生的变异改变了我们对多种癌症患者的治疗。我们相信采用MRI确定肿瘤变异的潜在可行性。以往确定肿瘤突变的惟一方法是：取出组织，通过两种实验方法之一检测变异是否存在。在本研究中，我们是用无创性方法进行确定。就我所知，这是采用MRI（或者其他影像技术）来准确预测人类肿瘤变异类型的首例报道。”

＂The field of cancer research has evolved to the point^1 where the identification of the mutations that cause tumors has changed how2 we treat patients in a number of cancers,＂ says Dr. Donald O＇Rourke, associate professor of neurosurgery at the University of Pennsylvania School of Medicine. Potentially, we believe we have a method that uses MRI to identify a tumor mutation. Historically tumor mutations have been identified in only one way： take the tissue out and examine it using one of two laboratory tests to see if^3 the mutation is present. In this study we＇ve done this identification noninvasively. To my knowledge^4 this is the first demonstration that an MRI, or any imaging technique, can accurately predict the type of mutation of a human tumor.