头孢呋新与头孢克罗序贯治疗小儿肺炎的临床分析

Clinical analysis of Cefuroxime sequential therapy of pediatric pneumonia.

目的比较静脉使用头孢呋新和口服头孢克罗序贯治疗和常规静脉用药在治疗小儿肺炎中的疗效、安全性、可行性及患儿的依从性。方法122例肺炎住院患儿，开始以头孢呋新75mg／（kg·d），分两次治疗。三天后临床改善者84例作为研究对象，随机分为两组，序贯治疗组45例口服头孢克罗20～40ms／（kg·d），分三次；常规治疗组39例，继续接受静脉用药治疗。结果从临床治愈率、症状、体征及X线改善情况来看，两组无显著差别，但序贯治疗组的住院日比常规组缩短2d。结论对最初静脉头孢呋新治疗反应良好的肺炎患儿。可以安全地转为口服的序贯治疗，该疗法将缩短住院时间。

Objective Comparison of intravenous and oral cefuroxime sequential therapy Cefaclor and conventional intravenous drug in the treatment of children with pneumonia about efficacy, safety, feasibility and compliance of children. Methods 122 cases of children hospitalized with pneumonia and began to Cefuroxime 75 mg/（ kg · d）, two times. Three days later, 84 cases of clinical improvement-for the study were randomly divided into two groups, sequential treatment group ,45 cases of oral cefaclor 20 -40 mg/（ kg· d）, three times ;39 cases of conventional therapy group continued to receive intravenous drug treatment. Results From the clinical cure rate, symptoms, signs and X - ray to improve the situation, no significant difference between the two groups, but the sequential treatment group than in the hospital two days to reduce the conventional group. Conclusion The initial intravenous cefuroxime good response to treatment in children with pneumonia can be safty converted to oral sequential therapy, the therapy will shorten the length of stay in hospital.