原发性甲状腺功能亢进手术治疗中腺体残留量的探讨

Gland residual volume in primary hyperthyroidism surgery

目的：探讨甲状腺大部分切除术后，腺体残留量与甲状腺功能（甲功）之间的相关因素。方法：近五年来选取80例不同时间由同一组医生手术，经术后病理证实的中、重度原发甲亢患者，记录手术前后的临床资料，术后随访1～5年。采用SAS软件对所得数据进行分析。结果：年龄、性别、是否用甲亢药物、甲亢的病程、术前T3、T4、FT3、FT4对术后甲功的影响比较差异无统计学意义，且不存在相关关系。甲状腺全量、残留量、残留率与术后甲功呈直线正相关。结论：甲状腺全量、残留量是影响术后甲功的重要因素。建议可应用多元回归方程公式，于术前或术中决定原发甲亢手术中甲状腺体的残留量。

Objective To evaluate the related factors of gland residual volume and thyroid function after subtotal thyroidectomy. Method Eighty cases treated by the same group of doctors in different time in recent 5 years, who were postoperative pathological confirmed of moderate or severe primary hyperthyroidism. The clinical data before and after surgery were recorded, and the patients were followed up for 1- 5 years. The data were analyzed with SAS software. Results The differences of impact of age, gender, whether taking anti - hyperthyroidism drugs, hyperthyroidism course and pre - operative T3, T4, FF3, FT4 on the postoperative thyroid function were not significant, and without correlation. Thyroid full volume, residual volume and residual rate showed linear positive correlation with the postoperative thyroid function. Conclusion Thyroid full volume and residual volume are the important factors impacting the postoperative residual thyroid function. Multiple regression equation formula can be applied preoperative or intraoperative in the decision of thyroid residual volume.