微电极导向苍白球腹后部切开术治疗帕金森病13例临床研究

Clinical report of microelectrode-guided posteroventral pallidotomy in treatment of Parkinson′s disease in 13 cases

目的:探讨苍白球腹后部切开术(PVP)治疗帕金森病(PD)的手术方法和临床效果。方法:采用坐标定位结合计算机计系统和MR I图像定位,应用微电极导向技术对13例原发性PD病患者实施了立体定向苍白球切开术。采用UPDRS评分量表对所有患者进行术前和术后的病情评分。结果:13例患者的震颤、僵硬及运动迟缓均得到明显改善,无其他特殊并发症发生。结论:苍白球切开术是治疗PD病患者的一种安全、有效的治疗方案,微电极记录是必要的。

Objective To explore the operative methods and effect of posteroventral pallidotomy （PVP） on Parkinson＇s disease （PD）. Method Using mieroeleetrode - guided technique and coordinate,combined with the computer planning system and MRI imaging location, 13 patients who suffered with primary PD underwent stereotaxie PVP. The preoperative and postoperative conditions in all the patients were assessed by the Unified Parkinson＇s Disease Rating Scale （UPDRS）. Results The muscle tremor, muscle rigidity and bradykinesia had obvious improvement in 13 patients. No other special complications existed. Conclusion PVP is a safe and efficient treatment for patients of PD. The mieroeleetrode recording is necessary.