摘要
评价了经化学和仿生改性后的4种钛试样的矿化性能。4种表面改性层分别为:锐钛矿纳米管(N),微/纳米结构(MN),纳米管表面接枝精氨酸-甘氨酸-天冬氨酸-半胱氨酸(NR),微/纳米结构表面接枝精氨酸-甘氨酸-天冬氨酸-半胱氨酸(MNR)。结果显示,表面矿化沉积物是羟基磷灰石,同样条件下,试样的诱导矿化能力依次是MNR﹥MN﹥NR﹥N。在生物材料表面构建微/纳米结构并接枝多肽是一种有效的表面改性方法。
The mineralization ability of 4 kinds of titanium implants after chemical and bionic modification was evaluated. The 4 kinds of surface modification layers were anatase nanotubes （N）, micro/nanostructure （MN）, nanotubes with grafted Arg-Gly-Asp-Cys （NR）, micro/nanostructure with grafted Arg-Gly-Asp-Cys （MNR）. Results show that the surface mineralization deposition is hydroxylapatite. Under the same condition, the inducing mineralization ability of the samples is MNR〉MN〉NR〉N. Combination of developing micro/nanostructure and grafting polypeptide is an effective way of surface modification for biomaterials.
出处
《稀有金属材料与工程》
SCIE
EI
CAS
CSCD
北大核心
2009年第8期1406-1409,共4页
Rare Metal Materials and Engineering
基金
国家自然科学基金(50871093)
教育部全国博士学位论文作者专项资金(200554)
关键词
钛
表面改性
微/纳米结构
多肽
矿化
titanium
surface modification
micro/nanostructure
polypeptide
mineralization
