儿童结核病并营养不良的体液免疫状况分析

THE RELATIONSHIP BETWEEN PROTEIN-MALNUTRITION AND HUMORAL IMMUNITY IN CHILDREN WITH TUBERCULOSIS

目的探讨结核病并营养不良患儿体液免疫功能状况。方法对2007年1月～2008年12月在本院儿科门诊治疗的结核病患儿体液免疫功能进行分析。结果①学龄前儿童结核患者并蛋白质营养不良较多(73.9%,p<0.05);②在营养不良组中,PPD皮试强阳性率60.0%、PPD-IgG阳性率39.5%,与对照组没有明显差异(p>0.05);③在营养不良组中,36%患儿血清IgA及IgG水平低于正常值。结论①在结核病患儿中学龄前儿童并蛋白质营养不良较多;②患儿营养状况对PPD试验和血清PPD-IgG测定影响不大;③并营养不良结核患儿其血清IgA和IgG水平没有增高,与其他结核病患儿相同。

Objective To study that the relationship between the protein - malnutrition and humoral immunity in children with tuberculosis. Methods To analyses the patients with tuberculosis for treatment in our out - patient department from Jan. 2007 to Dec. 2008. Results The patients with tuberculosis were more suffered from the protein - malnutrition in the preschool child group （73.9% ,p 〈0. 05）. The strong positive rate of PPD test was 60. 0% and the positive rate of PPD - IgG was 39.5% ,which was not distinctively different （p 〉 0. 05 ）. The serum IgA and IgG were low for 36% patients in the protein - malnutrition group. Conclusion The patients with tuberculosis were more suffered from the protein - malnutrition in the preschool child group. The nutrition condition in children tuberculosis can not effect the strong positive rate of PPD test and the positive rate of PPD - IgG. The serum IgA and IgG were not increase in children tuberculosis.