摘要
目的探讨血清半胱氨酸蛋白酶抑制剂C(Cystatin C)与乙型肝炎的关系。方法用颗粒增强透射免疫比浊法检测97例乙型肝炎患者及25例健康志愿者的血清Cystatin C水平,同时测其血清HBV-DNA(定量)、ALT、AST、TBIL、PT以及透明质酸(HA)、III型前胶原(PIIIP)、IV型胶原(CL-IV)、层粘连蛋白(LN)等。分析血清Cystatin C与临床类型及HBV-DNA、HBV-M、肝纤维化血清学指标间的关系。结果血清Cystatin C水平在不同临床类型的乙型肝炎间差异无统计学意义;Cystatin C与HBV-DNA(定量)、ALT、AST、TBIL、PT以及血清纤维化指标等不相关。结论血清Cystatin C与乙型肝炎的临床类型不相关。
Objective To explore the relationship between Serum cystatin C and hepatitis B.Methods The concentrations of serum cystatin C in 97 patients with hepatitis B were assayed by icropartical enhanced turbid-imetry and compared with those in 25 healthy persons as control group.Serum HBV-DNA（quantitative）,alanine aminotransferase（ALT）,aspartate aminotransferase（AST）,total bilirubin（TBIL）,prothrombin time（PT）,hyaluro-nic acid（HA）,Ⅲ procollagen type（PⅢP）,Ⅳ-type collagen（CL-Ⅳ）and laminin（LN）were assayed at the same time.Results There were no significant differences in cystatin C concentrations among the different clinical types of hepatitis B;cystatin C didn＇t correlate with HBV-DNA,ALT,AST,TBIL or PT;any significant correlation was not found between cystatin C and serum fibrosis indicators.Conclusion There are no significant correlation between cystatin C and the clinical types of hepatitis B.
出处
《现代实用医学》
2009年第7期693-695,F0002,共4页
Modern Practical Medicine
基金
宁波市科技局
宁波市卫生局基金
编号200539
