摘要
与通常的脱水缩合反应条件不同,而以H2O或以H2ODMSO(1∶2,体积比)为介质,加热下方酸与芳伯胺之间可顺利实现脱水反应.方酸与芳伯胺的摩尔比为1∶2.2时,主要生成双取代产物异方酰胺;在1∶1的情况下,主要生成单取代产物N芳基氮氧方酸.
The dehydration reaction between squaric acid and primary arylamine are easity formed when heated in H_2O or H_2ODMSO(1∶2,Volume ration),it is quite different from the normal condition of dehydration condensation reactions.Disubstituted isosquaramide was obtained as main product when the molar ratio of squaric acid to primary arylamine was 1.0∶2.2;and monoamide of squaric acid (Narylnitrogenoxosquaric acid) was obtained as main product when the ratio was 1∶1.So this synthetic reaction is a very simple and effective route for preparation of concerned compounds.
出处
《四川大学学报(自然科学版)》
CAS
CSCD
北大核心
1998年第4期596-600,共5页
Journal of Sichuan University(Natural Science Edition)
基金
四川省教委青年教师科研基金
关键词
缩合反应
酰胺
方酸
环丁烯二酮
condensation reaction,amides,squaric acid,cyclobutenedione,chemistry of squaric acid