包膜微气泡非线性与超声造影剂谐波特性的研究

Non-Linearity of Encapsulated Microbubble and Harmonics of Encapsulated Ultrasound Contrast Agent

对包膜超声造影剂 (ultrasoundcontrastagents ,以下简称UCA)的非线性特性进行了理论分析与模型仿真研究 ,对比研究了不同尺寸的理想气泡和包膜微气泡在不同频率超声场中的基波与谐波散射特性 ,研究结果对UCA的制备及其应用技术有重要价值 .UCA谐波特性实验结果直观地反映了白蛋白超声造影剂显著的非线性特性 ,该特性将为医学超声成像技术和相应基础研究开拓新的领域 .

Non-linearity of ultrasound contrast agent(UCA) is studied theoretically and using model analysis. The fundamental and second harmonics of ideal bubble and encapsulated microbubble are compared. Experiments detect appreciable non-linearity of albumin UCA that provides insights into medical ultrasound imaging technique and other prospects.