高热宁注射液的抗炎实验研究

Experimental study of anti-inflammatory action of Gaorening injection

目的:探讨高热宁注射液的抗炎作用机理。方法:通过对角叉菜胶所致大鼠足肿胀的抗炎实验和对角叉菜胶所致小鼠足肿胀中炎症介质PGE2含量的影响,探讨高热宁注射液的抗炎作用机理。结果:高热宁注射液能够抑制炎症性肿胀,抑制炎症介质PGE2的产生。结论:高热宁注射液具有明显的抗急性炎症效应,其抗炎作用主要是通过抑制炎症介质的产生而实现的。

Objective： To investigate the anti-inflammation actions of Gaorening injection.Methods：We observed the anti-inflammation action by rat metatarsal swelling experiments with carrageena,and the content of PGE2 in mice′shind paw after injecting carrageena.Results：Gaorening injection could reduce the capillary permeability of the inflammatory tissue and inhibit the inflammatory swelling andinhibit the yielding of inflammatory medium.Conclusion：Gaoreningin jection has obvious anti-inflammation action and anti-inflammation action.