转化糖注射液对合并有糖尿病的急性酒精中毒患者血糖的影响

Effect of Invert Sugar Injections on Blood Glucose of Patients with Acute Alcoholism and Diabetes

目的探讨转化糖对合并有糖尿病的急性酒精中毒患者血糖的影响。方法将40例合并有糖尿病的急性酒精中毒患者随机分为转化糖组、葡萄糖组两组各20例,分别输注5%转化糖、10%葡萄糖注射液500mL,于治疗前、输液后即刻、输糖液250mL时、输糖液结束时、输糖液后30min及2h监测血糖浓度。结果输液后即刻、输糖液中、后各时点葡萄糖组血糖均高于转化糖组(P<0.05),转化糖组血糖波动小于葡萄糖组(P<0.05)。试验前后心电图,血、尿常规,肝、肾功能,血尿酸均未出现与药物相关的变化。结论转化糖较葡萄糖对合并有糖尿病的急性酒精中毒患者的血糖浓度变化影响小,应用较葡萄糖注射液更为安全。

Objective To investigate the effect of invert sugar injections on blood glucose of patients with acute alcoholism and diabetes. Methods Forty patients of acute alcoholism with diabetes were randomly divided into invert sugar group and the glucose group ,which were 20 cases. Two Groups of patients were infused 500ml of 5% invert sugar injections, 10% glucose injection, respectively. The blood glucose concentration were monitored in the pre-treatment,immediate time of infusion-related, the time of infusion of 250ml, the end of infusion, 30min and 2h after the infusion. Results The blood glucose concentration of glucose group were higher than the invert sugar group in the immediate time of infusion-related, the time of infusion of 250ml, the end of infusion, 30min and 2h after the infusion （P 〈 0.05, P 〈 0.01 ）, and fluctuations in blood sugar were less than glucose group （P 〈 0.05）. Conclusion Invert sugar injections had less influence for the blood glucose concentration and more security than glucose injection.