肝动脉化疗栓塞术后联合射频热凝治疗乏血供肝癌

B-guided Radiofrenquency Ablation in Treating Lack Blood Advanced Large Liver Cancer after Transcatheter Arterial Chemoembolization Therapy

目的探讨晚期原发性乏血供大肝癌(直径>5cm)患者,先行肝动脉化疗栓塞(TACE),再行CT引导下经皮肝穿刺射频热凝(PRFA)治疗的疗效。方法分析我院2007年9月～2008年9月晚期原发性乏血供大肝癌患者46例,其中联合组28例,即先行TACE治疗,再行CT引导下PRFA治疗。治疗后1个月行CT增强扫描复查肿瘤坏死的情况,以评价肿瘤完全坏死率。结果经过治疗后肿瘤完全坏死率分别为70.5%,39.6%(P=0.024),两组坏死率有显著差异。结论晚期原发性乏血供大肝癌患者先行TACE治疗,再合理应用PREA治疗,较仅行TACE治疗能提供其疗效。

Objective To investigate the therapeutic effect of transcatheter arterial chemoemlization （TACE）,combined with percutaneous radiofrequency ablation （PRFA） in treating lack blood advanced large liver cancer. Methods 46 patients with primary advanced liver cancer were divided into TACE group and TACE＋PRFA group between September 2007 and September 2008. Results The complete necrosis ratesof tomors 70.5%, 39.6% （P=0.024）, there were significant statistical differences in the complete necrosis ratesof tomors. Conclusion B-guided radiofrenqueney ablation in treating lack blood advanced large liver cancer after transcatheter arterial chemoembolization therapy is effective.