2006-2007年云南省红河州流行性感冒监测结果与分析

Surveillance of influenza in Honghe prefecture,Yunnan,2006-2007

目的了解2006-2007年云南省红河州流行性感冒(流感)的流行特点,探讨优势株的变化。方法采集疑似流感患者咽拭子,接种于MDCK细胞于34℃CO2培养箱内进行病毒分离,培养液进行血凝试验,阳性标本进行分型鉴定。结果全年哨点医院共采集咽拭子标本991份,分离得到123株流感病毒,阳性率12.4%,其中H1N1 37株,H3N2 41株,Victoria 42株,Yamagata 1株,待定2株。各县(市)疾病预防控制中心采集疑似流感患者咽拭子56份,分离得到39株流感病毒,阳性率69.6%。均为B型Victoria系流感病毒。结论在2006-2007年监测年度中,2006年3-6月以B型Victoria系毒株为主,2006年7-9月以H1N1为主,2007年1-3月以H3N2为主。疑似流感疫情均为B型Victoria系。

Objective To analyze the epidemic features of influenza in Honghe prefecture from 2006 to 2007 and discuss the changes of the predominant strains of influenza virus. Methods Throat swabs derived from suspected influenza patients were inoculated into MDCK cells and cultured at 34 ℃ in a CO2 incubator for virus isolation. Hernagglutination test was then performed based on the culture medium, and serotyping was conducted for positive samples. Results A total of 911 throat swabs were collected in sentinel hospitals throughout the year and 123 strains of influenza virus were isolated （ 12.4% ）, among them 37 strains were H1N1 virus, 41 strains were H3N1 virus, 42 strains were B/Victoria lineage virus, one strain was B/Yamagata lineage virus and 2 strains were unspecified. A total of 56 swabs were collected from suspected patients by the centers for disease control and prevention in various counties and cities, and 39 strains of B/Victoria lineage virus were isolated （69.6%）. Conclusion In 2006, the predominant strain of influenza virus from March to June was B/Victoria lineage virus, and from July to September was H1N1 virus. In 2007, the predominant strain from January to March was H3N2 virus. All the strains isolated in suspected influenza epidemic were B/Victoria lineage virus.