摘要
滤泡性淋巴瘤的发生率居非霍奇金淋巴瘤发病率的第二位,临床上疾病发展呈惰性,主要表现为无痛性淋巴结肿大。预后因素包括滤泡淋巴瘤国际预后指数(FLIPI)、肿瘤组织免疫微环境。免疫化疗已成为滤泡淋巴瘤的一线治疗方法,滤泡淋巴瘤一经诊断即应开始治疗,观察等待策略仅限于少数选择病例。造血干细胞移植适用于复发、难治的病例。
Follicular lymphoma accounts for 22.1% of non-Hodgkin lymphoma. It is an indolent lymphoma. The clinical feature is lymphadenopathy with/without marrow involvement. The prognostic factors include follicular lymphoma international prognosis index (FLIPI) and tumor infiltrating immune cells. The first-line therapy is immunochemotherapy with rituximab. In patients with refractory/relapes disease, stem cell transplantation is the choice.
出处
《白血病.淋巴瘤》
CAS
2009年第8期496-499,共4页
Journal of Leukemia & Lymphoma
关键词
淋巴瘤
滤泡型
预后
治疗
Lymphoma, follicular
Prognosis
Therapy