藏药短管兔耳草中1个新苯乙醇苷类化合物

A new phenylethanoid glucoside from Lagotis brevituba

目的:对藏药短管兔耳草的化学成分进行研究。方法:用硅胶柱色谱、聚酰胺柱色谱和半制备HPLC分离纯化化合物,并用波谱学方法进行结构鉴定。结果:从藏药短管兔耳草的醋酸乙酯提取物中分离得到2个化合物,经鉴定均为苯乙醇苷类化合物。结论:化合物1为新化合物,命名为兔耳草苷A(lagotiside A),化合物2为毛蕊花糖苷。

Objective： To study the chemical constituents of Lagotis brevituba. Method： The chemical constituents were isolated and purified by silica gel column chromatography, polyamide column chromatography, and semi-preparative HPLC, and their structures were elucidated on the basis of analysis of IR ,NMR, 2D-NMR, and MS spectra. Result： Two compounds were obtained and were identified as phenylethanoid glucosides, lagotiside A （1） and acteoside （2） , respectively. Conclusion： Compound 1 is a new compound and named as lagotiside A.