腺苷脱氨酶测定在良恶性胸腔积液鉴别中的应用

The Application of Adenosine Deaminase in the Identification between Benign and Malignant Pleural Effusion

目的:探讨腺苷脱氨酶活性测定在良恶性胸腔积液鉴别中的应用。方法:对156例结核性胸腔积液和60例恶性胸腔积液标本进行腺苷脱氨酶测定,同时测定血清腺苷脱氨酶活性。结果:结核性胸腔积液患者的腺苷脱氨酶活性(91.2±22.4)U/L明显高于血清(21.8±5.8)U/L,也明显高于恶性胸腔积液(22.2±5.6)U/L,两者比较差别有显著意义(P<0.01)。结论:胸腔积液腺苷脱氨酶活性测定可以作为鉴别良恶性胸腔积液的指标,尤其在结核性胸膜炎中有临床诊断价值。

Objective： To investigate the application of Adenosine Deaminase （ADA） in the identification between benign and malignant Pleural effusion. Methods： To assay the activity of ADA in specimen and serum between the patients of 156 tuberculous pleural effusions and 60 malignant pleural effusion. Results ： The activity of ADA in tuberculous pleural effusion （91.2±22.4）U/L is super than serum （21.8±5.8）U/L and malignant pleural effusion （22.2±5.6）U/L, the difference is significant （P〈0.01）. Conclusion： The activity of ADA could serve as a marker in the identification between benign and malignant Pleural effusion, especially has the clinical diagnosis value in tuberculous pleuritis.