宫颈薄层液基细胞学检测2435例结果分析

Analysis of Results of 2435 Cases Thin Prep Cytology Test

目的报告我科对TCT检测异常的335例患者行活体病理组织学检查的结果及相关发病因素的分析。方法回顾性分析2005年2月-2009年2月我科宫颈新柏氏TCT检查结果。TCT检查异常者行活体病理组织学检查,并对其年龄、好发年龄段、HPV感染率等因素进行分析。结果TCT检查异常者2435例,宫颈炎1435例,占61.2%;C IN1 231例,占9.9%;C IN2 301例,占12.8%;C IN3 294例,占12.5%;磷癌（SCC）49例,占2.1%;腺癌（AC）28例,占1.2%;粘液癌（MC）7例,占0.3%。各种宫颈疾病的好发年龄段为26~50岁。2435例TCT检测异常的病例中,HPV检出476例,占20.3%。结论我院TCT检查与病理诊断的符合率,HPV感染率,TCT检查与病理活检癌的准确率,年龄分析,好发年龄段等各指标与同行一致。

Objective To report the results of histopathological examination on 335 cases of patients with abnormal TCT test results and to analyze the related pathogenic factors.Methods We retrospectively analyzed the results of ThinPrep Cytology Test performed in our department from February,2005 to February,2009.All the patients with abnormal TCT test results were inspected by method of in vivo histopathology.At the same time,the age,predilection age stage and HPV infection rate were also take into consideration.Results Among the 2435 cases with abnormal results of TCT test,1435 were with cervicitis and account for 61.2%, 231 with CIN1 and account for 12. 8%, 301 with CIN2 and account for 12. 8% , the cases of squamous carcinoma, adenocarcinoma and mucinous carci- noma were 49, 28 and 7, and account for 2. 1% ,1.2% and 0.3% , respectively. All kinds of cervical diseases happened most at the age stage of 26 -50 in the 2435 cases we analyzed were detected with HPV infection 476 cases, with the detection rate of 20.3%. Conclusion The results our hospital got was consistent with our counterparts in the following aspects： the consistency between TCT test and pathological diagnosis, the accuracy of TCT test and in vivo pathological examination for cancer detection, HPV infection rate and age stage cervical diseases happened most.