河南省病毒性脑炎病原谱研究初报

Preliminary Study on Viral Etiology of Viral Encephalitis in Henan Province

目的了解河南省病毒性脑炎的病原种类及其分布。方法采用ELISA方法对2005年我省临床诊断为病毒性脑炎患者的急性期血清和脑脊液标本检测病毒特异性IgM抗体。结果209例患者中的193例(92.3%)检测出病毒特异性IgM抗体,构成顺序依次为柯萨奇病毒、埃可病毒、腮腺炎病毒、单纯疱疹病毒、乙脑病毒、EB病毒和水痘-带状疱疹病毒。结论肠道病毒、腮腺炎病毒、单纯疱疹病毒、乙脑病毒是我省病毒性脑炎的主要病原。

Objective To study the viral etiology and distribution of viral encephalitis in Henan province.Methods Colletcted serum and cerebrospinal fluid samples of 209 patients with viral encephalitis or menigitis from May1 2005 to October31 2005,stored at-20℃ or-70℃.Enzyme-linked immunosorbent assays were used for detection of IgM antibody to viral etiology of viral encephalitis.Results IgM antibody was positive in 193 of 209（92.3%） cases.form high to low there are Cox、Echo、Mumps、HSVⅠ、JEV、EBV、VZV.Conclusion According to the study, Evs, Mumps, HSVⅠ ,JEV are the major viral etiology of viral encephalitis in Henan province.