摘要
胆道癌唯一可治愈的方法是完全的手术切除,然而仅有10%的患者才适合手术,在这些患者中,肿瘤复发率又很高,所以,对于大部分胆道系统癌患者来说,全身化疗就成为一种主要的治疗方法。虽然Ⅲ期临床随机研究很少,但是一致性的一线化疗方案正在出现,包括经典的细胞毒药物化疗和很有发展前景的靶向治疗。
Complete surgical resection offers the only chance for cure for biliary tract cancers; However,only 10% of patients are considered surgical candidates. Among those patients who undergo "curative" resection, recurrence rates are high ; thus, for the majority of patients with biliary tract cancer, systemic chemotherapy is the main treatment plan. Patients with unresectable or metastatic biliary tract cancer have a poor prognosis, and median overall survival time is less than one year. Despite lack of randomized phase Ⅲ data, consensus first-line systemic therapy is emerging,including classic cytotoxic chemotherapy and targeted therapy.
出处
《国际肿瘤学杂志》
CAS
2009年第8期619-621,共3页
Journal of International Oncology
基金
基金项目:山东省科技厅攻关项目(2007GG20002042)
关键词
胆道肿瘤
药物疗法
Biliary tract neoplasms
Drug therapy