Lugol’s液染色对食管癌前病变的诊断价值

Efficiency of Lugol's solution in the diagnosis of esophageal precancerous lesions

目的:探讨lugol’s液染色对食管癌前病变的的诊断价值。方法:150例食管粘膜异常表现的患者,用2%的Lugol’s液染色,然后取活检送病理组织学检查。此外,对354例未染色的活检结果进行对比。结果:在染色的150例患者中,27例诊断为非典型增生。11例为肠化生,黏膜内癌3例,与未染色活检相比,诊断率明显提高(p<0.01)。结论:内窥镜下Lugol’s液染色可明显提高食管癌前病变及食管早期癌的检出率。

Objectives：To evaluate the effectiveness of Lugol＇ s solution staining in the diagnosis of esophageal precancerous lesions. Methods： 150 patients with abnormal esophageal mucosa appearance were biopsied after Lugol＇s solution staining. Results： In 150 patients with abnormal esophageal mucosa appearance, 27 patients were diagnosed with esophageal dysplasia, 11 patients were diagnosed as Barrett＇s esophagus, and 3 patients were diagnosed as early esophageal cancer. It is signilicantly higlier than that without Lugol＇ssolution staining. Conclusions： Biopsy of the esophageal mucosa after Lugol＇s solution staining has a high rate in diagnosing the esophageal precancerous lesion and early esophageal cancer.