6Hara Y, Sato E, Miyagishi A, et al. Synthesis and β-adrenergic blocking action of a new thiazolylthiopropanolamine derivative [J]. JPharm Sci, 1978, 67 (9): 1334-1335.
7Alexander M, Bradshaw, Ian H, et al. Heterocyclic compounds, processes for their preparation and their use: EP, 0021840 [P]. 1981-07-01.
8Toshihiko H, Takarazuka. Process for producing 5-carboxy-2- acetylthiophene: US, 4130566 [P]. 1978-12-19.
9Goda H, Kawamura M, Kato K, et al. Novel thiophene derivatives and methods for producing the same: EP, 0245835 [P]. 1987-11-19.
10Kuwajima I,Suzuki Y,Otsuka K,et al.Effects of alpha,beta-blocker,on 24 h blood pressure-difference between elderly and younger hypertensive patients[J].J Clin Pharm Ther,1993,18(4):275.