升白快煎剂治疗白细胞减少症临床疗效观察

A Clinical Observation on the Leukopenia Treated with Shengbaikuai Decoction

目的 :研究开发经口服途径作用快、药效高的升白细胞新药。方法 :将 90例血液恶性疾病化疗后白细胞减少患者分为 3组 ,即升白快煎剂观察组、升白安片对照组和空白组进行疗效观察和对比。并对 2 5例非化疗组患者进行用药前后和 3周后观察。结果 :观察组白细胞 (WBC)计数、中性粒细胞 (ANC)计数治疗后和两周后较对照组、空白组增高 (均P <0 0 1 )。观察组两周后显效率为 60 0 %、总有效率为 80 0 % ,与对照组、空白组的疗效相比有显著性差异 (均P <0 0 0 1 )。 2 5例非化疗组患者治疗后、3周后WBC、ANC较治疗前明显增加(均P <0 0 0 1 ) ,3周后显效率为 64 0 % ,总有效率为 80 0 %。结论 :初步证明升白快煎剂的升白细胞作用具有疗效较高、作用快、疗效确切和无明显副作用等特点。

Objective: To study the effective orally taken medicine in treating the leukopenia. Methods: ninety cases of leukopenia induced by chemotherapy were divided into 3 groups. They were test group treated with Shengbaikuai Decoction (SBK), control group and blank group. Their efficacies were compared with each other, 25 cases with nonchemotherapy were also observed. Results: WBC count and absolute neutrophil count (ANC) in test group were higher than those of other groups immediately after treatment and 2 weeks later (P<0 01). The marked effective rate and total effective rate of test group after 2 weeks were 60.0% and 80.0% (P<0 001) respectively, which were significantly higher than those of other groups. WBC and ANC count after treatment and 3 weeks later were higher than those before treatment in nonchemotherapy group (P<0 001). The marked effective rate and total effective rate 3 weeks later were 64.0% and 80.0% respectively. Conclusions: SBK could increase WBC count rapidly and definitely without apparent side effect.