急性咽炎、扁桃体炎的细菌学特征及地喹氯铵口含片(泰乐奇)的疗效观察

Microbiology of acute pharyngitis and acute tonsillitis and treatment with Taileqi troches

为探讨地喹氯铵口含片（商品名：泰乐奇）治疗急性咽炎、急性扁桃体炎的效果，对100例此种患者作咽拭细菌学培养，同时，随机将患者分成两组，观察以地喹氯铵为主要成分的泰乐奇口含片和羟氨苄青霉素的疗效并进行对比。结果表明，此种患者的主要致病菌为β-溶血性链球菌、肺炎克雷伯菌、金黄色葡萄球菌；且部分检出产黑色素类杆菌、消化链球菌等厌氧菌。说明厌氧菌在咽部感染性疾病发病机制中起重要作用。对于早期和轻型急性咽炎、急性扁桃体炎患者，单独使用地喹氯铵口含片有效率为86％，与口服羟氨苄青霉素疗效（88％）相近；且地喹氯铵口含片口感舒适，服用方便，无一例出现不良反应，在临床有较好的应用价值。

A qualitative analysis of microflora from pharynx of 100 cases of acute pharyngitis and acute tonsillitis was per formed. These patients were randomly divided into two groups so as to assess treatment effeet of Taileqi troches vs Amoxycillin. Results showed that β-hemdytic streptococcus, klebsiella pneumoniae, staphylococcus aureus were the most common organisms causeing diseases. The predominant anaerobic organisms were bacteroides melaninogenicus,eptostrep. These findings suggest that anaerobic bacteria may play a pathogenic role in infection of the phargnx. The effective rate of treatment with troche alone were 86 percent,roughly consistent with Amorycillin group. No adverse effect was oberved.