新生儿缺氧缺血性脑病远期预后分析

A long-term follow-up of neonates with hypoxicischemic encephalopathy

目的了解新生儿颅内出血及缺氧缺血性脑病患儿远期预后。方法对４１例存活者进行随访，采用韦氏法及绘人法测定智商（ＩＱ），同时进行体格发育和神经系统、视力、听力检查。结果１２例遗留各种类型神经系统后遗症，其中５例重度残废。结论远期预后与急性期临床分型及危重指标数量密切相关。早期诊断、早期干预补救对部分智力落后患儿有效。

Objective To study the longterm prognosis of the newborns with intracranial hemorrhage and hypoxic ischemic encephalopathy. Methods Fortyone survivors of neonates with intracranial hemorrhage and hypoxicischemic encephalopathy were followed up for 68 years. The IQ was estimated by using Wechsler Intelligence Scale for Children (WISCCR)。 Physical and mental development, vision and hearing were also examined. Results Twelve survivors suffered from the sequelae of nervous system of various kinds, of whom 5 were seriously crippled. Conclusion The longterm prognosis correlated closely with the clinical classification in the acute period and the risk index. Early diagnosis and preventive intervention are effective in improving the memtal retardation, but can not change the prognosis in neonates with serious cerebral injury.