急性脑血管病与睡眠呼吸障碍相关性的临床观察

Correlation between acute cerebrovascular disease and sleep-disordered breathing： a clinical observation

目的探讨急性脑血管病与睡眠呼吸障碍之间的关系。方法选择95例急性脑血管病患者作为研究对象，并选择同期年龄、性别、体质指数相当的健康体检者作为对照组，均行全程多导睡眠监测。结果病例组患者睡眠呼吸障碍发病率为65．3％，健康对照组为5．4％（P〈0．01），而且病例组睡眠效率低下，睡眠结构紊乱，睡眠呼吸暂停低通气指数显著高于对照组[（30．3±15．4）次/h对（4．2±6．5）次/h，P〈0．01]。结论睡眠呼吸障碍与急性脑血管病的发病、神经功能损伤程度与恢复有关，对其进行干预对脑血管病的预防、治疗和康复预后具有重要的意义。

Objective To investigate the relationship between acute cerebrovascular disease and sleep-disordered breathing, Methods Ninety-five patients with acute cerebrovascular disease were selected as study objects, and their age, sex and body mass index matched healthy subjects were used as control group at the same time period. Full polysomnography monitoring was performed in all the patients. Results The incidence of sleep-disordered breathing in the case group was 65.3%, and in the healthy control group was 5.4% （P 〈0.01）, and that the sleep efficiency was lower and disordered in the case group. The apnea-hypopnea index was significantly higher than that in the control group （30. 3 ± 15.4 times/h versus 4. 2 ± 6. 5 times/h, P 〈 0.01）. Conclusions The sleep-disordered breathing and the onset of acute cerebrovascular disease were associated with the degrees of neurological injury and recovery. The intervention on them has an important significance in the prevention, treatment and rehabilitation prognosis of cerebrovascular diseases.