无抽搐电痉挛治疗难治性抑郁症33例效果观察及护理

Observation on the effect of modified ECT in the treatment of 33 patients with refractory depression and nursing care

目的:探讨无抽搐电痉挛治疗难治性抑郁症的效果及护理方法。方法:将65例难治性抑郁症患者随机分为两组,研究组33例采用无抽搐电痉挛治疗,对照组32例采用传统抗抑郁药物治疗。共观察4周,在治疗前及治疗第1周末、第2周末、第4周末分别采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、副反应量表(TESS)评定疗效及不良反应。结果:治疗第1周末、第2周末及第4周末,研究组HAMD及HAMA评分均显著低于对照组,差异均有显著性(P(0.05)。研究组未出现严重不良反应。结论:无抽搐电痉挛治疗配合有效的护理是治疗难治性抑郁症快速、有效、安全的首选方法之一。

Objective ： To discuss the effect of modified electroconvulsive therapy （ECT） and nursing methods in the treat- ment of refractory depression. Methods ： 65 patients with refractory depression were randomly divided into study group （ n = 33 ） and control group I n = 32 ）. Modified ECT was applied in study group and traditional antidepressant medication was used in control group. Hamilton Depression Rating Scale （ HAMD ）, Hamilton Anxiety Rating Scale （ HAMA ） and Treatment Emergent Symptom Scale （ TESS ） were adopted to respectively assess the efficacy and adverse reactions before treatment and at the end of the first, second and fourth week. Results ： The scores of HAMD and HAMA in study group were significantly lower than that in control group at the end of 1st, 2nd and 4th week after treatment （ P 〈 0.05 ）. No serious adverse reactions occurred in study group. Conclusion ： Modified ECT combined with effective nursing care is one of fast, effective, safe and preferred therapies in the treatment of refractory depression.