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一种快速检测四种毒品的测试系统 被引量:1

Multianalytic Assay System for Drug of Abuse
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摘要 一种在8分钟内检测四种毒品的方法被开发出来.这种方法简单,快速,准确,可以一次测出尿样中是否含有吸毒者常用的四种毒品代谢物THC(l-nor-Δ-9-tetrahydrocannabirol-9-carboxylicacid)、COC(cocaine)、MOR(morphine)、AMP(amphetamine),这种测试的毒品浓度截止点分别为THC:50ng/ml,COC:300ng/ml,MOR:300ng/mlAMP:1000ng/ml.当尿样中毒品浓度在50%和150%截止点浓度时,本测试方法的准确率大于99%,尿液中可能存在会和测试试剂起交叉反应的51种物质被证明对本测试系统无干扰作用.通过气相色谱/质谱证实是阳性的尿样经本测试系统测定,结果符合率大于或等于97%.  8min immunoassay system was developed to screen simultaneously four different classes of drug of abuse,namely ,THC,COC,MOR and AMP. The cutoff concentration for THC,COC,MOR and AMP are 50 ng/ml,300 ng/ml,300 ng/ml and 1000 ng/ml respectively. The accuracy was over 99% for urine samples with the 50% and 150% cutoff concentrations.51 compounds have been tested and proved to cause no interference.Over 97% of gas chromatography and mass spectrography confirmed positive urine samples were also shown positive results with the multianalytic assay system.
出处 《科技通报》 1998年第4期265-269,共5页 Bulletin of Science and Technology
关键词 毒品 测试系统 THC COC MOR AMP Conjugate, Cutoff, Crossreactivity
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