摘要
目的观察重症哮喘急性发作期无创正压通气(NPPV)的临床疗效。方法14例重症哮喘急性发作期患者使用双水平无创正压呼吸机进行治疗,检测治疗前及治疗1小时、2小时外周动脉血氧分压(PaO2)、二氧化碳分压(PaCO2)、pH变化。结果治疗1小时后,pH(7.33±0.33),PaCO2(57.45±7.79)mmHg,PaO2(83.25±9.36)mmHg,与治疗前比较,差异无显著性意义(P>0.05);治疗2小时后,PaO2为(87.55±7.49)mmHg,较治疗前明显升高(P<0.05),而PaCO2、pH值与治疗前差异无显著性意义(P>0.05)。结论NPPV对重症哮喘急性发作期的低氧血症有一定的疗效,而对CO潴留、呼吸性酸中毒的疗效有限。
Objective To observe the clinical effect of non-invasive positive pressure ventilation in patients with severe asthma. Methods 14 patients with severe asthma received non-invasive positive pressure ventilation treatment, the pH,PaO2 and PaCO2 from periphery arterial blood at the time of pre-ventilation, 1 hour and 2 hours after ventilation were investigated. Results Compared with pre-treatment, the value of PaO2 two hours after ventilation was increased significantly ( P 〈 0. 051 , but PaCO2 and PH had no significant change( P 〉 0.05 ). Conclusions In the patients with severe asthma ,NPPV can transiently relieve the hypoxygemia , but little effect on improving PaCO2 and pH.
出处
《实用医院临床杂志》
2009年第4期110-111,共2页
Practical Journal of Clinical Medicine
关键词
无创正压通气
重症哮喘
替代性治疗
Non-invasive positive pressure ventilation
Severe asthma
Replace treatment