期刊文献+

重症哮喘无创正压通气临床疗效观察 被引量:4

Clinical investigation of non-invasive positive pressure ventilation in patients with severe asthma
下载PDF
导出
摘要 目的观察重症哮喘急性发作期无创正压通气(NPPV)的临床疗效。方法14例重症哮喘急性发作期患者使用双水平无创正压呼吸机进行治疗,检测治疗前及治疗1小时、2小时外周动脉血氧分压(PaO2)、二氧化碳分压(PaCO2)、pH变化。结果治疗1小时后,pH(7.33±0.33),PaCO2(57.45±7.79)mmHg,PaO2(83.25±9.36)mmHg,与治疗前比较,差异无显著性意义(P>0.05);治疗2小时后,PaO2为(87.55±7.49)mmHg,较治疗前明显升高(P<0.05),而PaCO2、pH值与治疗前差异无显著性意义(P>0.05)。结论NPPV对重症哮喘急性发作期的低氧血症有一定的疗效,而对CO潴留、呼吸性酸中毒的疗效有限。 Objective To observe the clinical effect of non-invasive positive pressure ventilation in patients with severe asthma. Methods 14 patients with severe asthma received non-invasive positive pressure ventilation treatment, the pH,PaO2 and PaCO2 from periphery arterial blood at the time of pre-ventilation, 1 hour and 2 hours after ventilation were investigated. Results Compared with pre-treatment, the value of PaO2 two hours after ventilation was increased significantly ( P 〈 0. 051 , but PaCO2 and PH had no significant change( P 〉 0.05 ). Conclusions In the patients with severe asthma ,NPPV can transiently relieve the hypoxygemia , but little effect on improving PaCO2 and pH.
作者 孙晓燕 陈庆
出处 《实用医院临床杂志》 2009年第4期110-111,共2页 Practical Journal of Clinical Medicine
关键词 无创正压通气 重症哮喘 替代性治疗 Non-invasive positive pressure ventilation Severe asthma Replace treatment
  • 相关文献

参考文献4

二级参考文献23

  • 1陈萍,高燕,马壮,赵海涛,槐永军.应用机械通气治疗危重哮喘13例临床分析[J].中国实用内科杂志,2005,25(2):115-117. 被引量:9
  • 2Ranicri VM,Giuliani R,Cinnclla G,et al.Physiologic effects of positive end-expiratory pressure in patients with chronic obstructive pulmonary disease during acute ventilatory failure and controlled mechanical ventilation [J].J Am Rev Respir Dis,1993,147:5~131
  • 3Oku K, Kuboyama K, Sai.ar P, et al. Cerebral and systemic arteriovenous oxygen monitoring after cardiac arrest. Inadequate cerebral oxygen delivery. Resuscitation, 1994,27 : 141 - 152.
  • 4Organized jointly by the American Thoracic Society, the European Respiratory Society, the European Society of Intensive Care Medicine, et al. International Consensus Conferences in Intensive Care Medicine: noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med, 2001,163:283- 291.
  • 5British Thoracic Society Standards of Care Committee. Noninvasive ventilation in acute respiratory failure. Thorax,2002, 57: 192-211.
  • 6Paus-Jenssen ES, Reid JK, Cockcroft DW, et al. The use of noninvasive ventilation in acute respiratory failure at a tertiary care center. Chest,2004,126 : 165-172.
  • 7Liesching T, Kwok H, Hill NS. Acute applications of noninvasive positive pressure ventilation. Chest, 2003, 124:699-713.
  • 8Ambrosino N, Foglio K, Rubini F, et al. Non-invasive mechanical ventilation in acute respiratory failure due to chronic obstructive pulmonary disease: correlates for success. Thorax, 1995,50:755-757.
  • 9Ferrer M, Esquinas A, Leon M, et al. Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial. Am J Respir Crit Care Med, 2003, 168 : 1438-1444.
  • 10Barbe F, Togores B, Rubi M, et al. Noninvasive ventilatory support does not facilitate recovery from acute respiratory failure in chronic obstructive pulmonary disease. Eur Respir J, 1996, 9: 1240-1245.

共引文献3612

同被引文献22

引证文献4

二级引证文献80

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部