老鹳草提取物治疗低位直肠癌的临床观察及机理探讨

Therapeutical effect of Geranium sibirium extract on low rectal carcinoma

目的:探讨低位直肠癌综合治疗方法,减少局部并发症,提高生存质量。方法:采用外照射,近距离后装治疗,老鹳草提取物口服并腔内外微波加温综合治疗低位直肠癌30例。结果:本组病例4年随访期间,除4例局部复发和5例远处转移,4年生存率和无瘤生存率分别为87%(26/30例)和83%(25/30例)。结论:低位直肠癌的保守治疗,可通过单项减量,综合治疗,降低局部并发症和复发率,从而提高患者的生存质量。

AIM： To investigate the therapeutical effect of Geranium sibirium extract on the patients with low rectal carcinoma, reserving anus reducing complication and increasing survival rate. METHODS： The treatments included extrasomatic radiotherapy near to tumor, intracavity and extracavity microwave diathermy as well as oral ad- ministration of Geranium sibirium extract . All the 30 patients were treated. RESULTS： The four-year follow -up showed that except 4 cases had local recurrence and 5 cases had distant metastasis, four-year survival rate and tumor-free survival rate were 86.7% （26/30） and 83% （25/30）,respectively. CONCLUSION： With general treatment and low dose radiotherapy , the therapeutics of reserving anus in low rectal carcinoma may increase survival quality , reduce complication and recurrence rate.