白速消皮肤黏膜消毒液阴道黏膜刺激性研究

Study on the Vaginal Mucosa Irritation of Baisuxiao Skin Mucosa Disinfective Liquid

目的:探讨白速消皮肤黏膜消毒液对阴道黏膜的刺激作用,并进行安全性评价。方法:依照《消毒技术规范》(2002版),进行一次、多次阴道黏膜刺激性试验,评价该消毒液对家兔的阴道黏膜刺激性影响。结果:一次阴道黏膜刺激性试验的阴道黏膜刺激指数为0.5,多次阴道黏膜刺激性试验的阴道黏膜刺激指数为1.6。结论:白速消皮肤黏膜消毒液对家兔一次、多次阴道黏膜刺激性试验结果为无刺激性、极轻刺激性,未见黏膜毒性。

Objective： To explore the vaginal mucusa irritation of Baisuxiao skin mucosa disinfective liquid and to make its safety assessment. Methods： According to the Technical Standard For Disinfection（2002）,The single vaginal and the sequential mucosa irritation tests were carried out to evalute the vaginal mucosa irritations on the rabbits by means of the grading table of the vaginal mucosa irritation degree. Results： The vaginal mucosa irritation indexes of the single and sequential vaginal mucosa irritation test were 0.5,1.6. Conclusion：Baisuxiao skin mucosa disinfective liquid has no vaginal mucosa irritation and imponderability vaginal mucosa irritation on rabbits and causes no dermal toxicity.