期刊文献+

骨肉瘤的治疗进展 被引量:2

Therapeutic Progresses about Osteosarcoma
下载PDF
导出
摘要 骨肉瘤是一种临床常见恶性骨肿瘤,尽管骨肉瘤的治疗有了长足的进展,近80%患者能保留病肢,且5年生存率由20%左右提高到近80%,但仍有半数以上的患者死于骨肉瘤的转移和复发。治疗上采用术前、后辅助化疗,假体植入,自身骨移植及骨肉瘤灭活肢体再植等方法使保肢术成为可能,生物调节、免疫、基因治疗的应用将为骨肉瘤治疗提供了新的希望途径。 Osteosarcoma is one kind of clinical common malignant bone tumors, although significant progress has been achieved in its treatment,such as,nearly 80% patients can retain sickness extremity, and survival rate is enhanced from 20% to nearly 80% , there is still more than half patient who will be died from its metastasis and recurrence. Many therapeutic mebods, such as assistant chemotherapy before and after surgery, prosthesis implantation, bone grafting and its inactivated osteosarcoma limb rcimplantation ,will provide possibility for limb saving. Biological regulation, immunology, gene therapy will provide new therapeutic possibility for osteosarcoma.
作者 孟琳 李新志
出处 《医学综述》 2009年第16期2431-2434,共4页 Medical Recapitulate
关键词 骨肉瘤 治疗 进展 Osteosarcoma Treatment Progress
  • 相关文献

参考文献1

共引文献40

同被引文献22

  • 1崔树波.骨肉瘤中西医结合治疗的进展[J].中国中西医结合急救杂志,2005,12(6):382-384. 被引量:4
  • 2王威.骨肉瘤治疗现状与展望[J].临床合理用药,2012,5(16):96.
  • 3Jaffe N.Osteosarcoma:review of the past,impact on the future.The American experience[J].Cancer Treat Res,2010,98(152):239-262.
  • 4Marian CO,Wright WE,Shay JW.The effects of telomerase inhibition on prostate tumor-initiating cells[J].Int J Cancer,2010,127(2):321-331.
  • 5Dutour A,Monteil J,Paraf F,et al.Endostatin cDNA/cationic liposome complexes as a promising therapy to prevent lung metastases in osteosarcoma:study in a human-like rat orthotopic tumo[J].Mol Ther,2005,11(2):311-319.
  • 6Roux BG,M6chinaud F,Gay-Andrieu F,et al.Successful triple combination therapy of disseminated absidia corymbifera infection in an adolescent with osteosarcoma[J].J Pediatr Hematol 0ncol,2010,32(2):131-133.
  • 7Oka K,Yakushiji T,Sato H,et al.The value of diffusion-weighted imaging for monitoring the chemotherapeutic response of osteosarcoma:a comparison between average apparent diffusion coefficient and minimum apparent diffusion codlicient[J].Skeletal Radiol,2010,39(2):141-146.
  • 8Tang N,Song WX,Luo J,et al.Osteosarcoma development and stem cell differentiation[J].Clin Orthop Relat Res,2008,466(9):2114-2130.
  • 9Higashiyama M,Okami J,Maeda J,et al.Differences in chemosensitivity between primary and paired metastatic lung cancer tissues:In vitro analysis based on the collagen gel droplet embedded culture drug test(CD-DST)[J].J Thorac Dis,2012,4(1):40-47.
  • 10Lin F,Zheng SE,Shen Z,et al.Relationships between levels of CXCR4 and VEGF and blood-borne metastasis and survival in patients with osteosarcoma[J].Med Oncol,2010,23(6):462-468.

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部