摘要
随着基因组学和蛋白质组学的进步，新的肿瘤标志物层出不穷，新发现的前列腺癌标志物有人激肽相关肽酶2、基质金属蛋白酶、前列腺特异性膜抗原、前列腺癌抗原3、早期前列腺抗原、胰岛素样生长因子与结合蛋白、尿激酶纤溶酶原激活物及其受体、α甲基乙酰辅酶A限速酶、转化生长因子β1、前列腺分泌蛋白94、E-钙黏素、白细胞介素配体和受体和肿瘤抗原的自身抗体。本文对这些新标志物予以综述。
With the development of genomies and proteomies, new tumor markers are increasing. The new found markers for prostate eaneer includes many kinds, such as kallikrein2, matrix metalloproteinase, prostate member specific antigen, prostate cancer antigen 3, early prostate cancer antigen, insulin-like growth factor, urokinase plasminogen aetivator, a-methyaeyl-CoA rasemase, transforming growth factor-β1 , prostate secretory protein 94, e-eadherin ,interlukine-6 and its soluble receptor, autoantibody of tumor antigen and so on. This article reviews the related markers of prostate cancer.
出处
《医学综述》
2009年第16期2437-2440,共4页
Medical Recapitulate
关键词
标志物
前列腺癌
早期诊断
特异性
敏感性
Biomarker
Prostate cancer
Early diagnosis
Specificity
Sensitivity
