卵巢过度刺激综合征的研究进展

The Progress in Ovarian Hyperstimulation Syndrome

卵巢过度刺激综合征是应用外源性促性腺激素促排卵引起的医源性并发症，是卵巢对促性腺激素刺激所表现出的过度反应。由于过多的卵泡发育而引起双侧卵巢增大及血管通透性增加，最终导致血管内液体漏出、胸腔积液、腹水、血液浓缩、电解质紊乱、肝肾功能损害等，严重者危及生命。近年来，随着生殖辅助技术的不断开展和促超排卵技术的广泛应用，该综合征的发病机制、临床诊断、治疗和预防的研究也获得很大进展。

Ovarian hyperstimnlation syndrome （OHSS） is an＇iatrogenie complication due to gonadotropin from foreign origin. It is ovarian excessive reaction to gonadotropin and characterized by increase in capillary permeability of the mcsothelial surface due to excessive follicles development. Its clinical syndrome includes massive ovarian enlargement, ascites, pleural effusion, haemoconcentration phenomena, Electrolytes disorder,liver and renal failure and so on. Serious case threatens life. In recent years, the human assisted reproductive technology constantly was developed and applied widely to control ovarian hyperstimulation, This article gave an overview about the progress in pathogenesis, diagnose, treatment and the measures to OHSS.