摘要
目的分析左氧氟沙星联合卷曲霉素方案治疗耐多药结核病(MDR-TB)的疗效。方法124例耐多药结核病患者随机分为治疗组和对照组,每组62例。化疗方案治疗组为3VCLTHZ/6CVL,对照组为3LKZTHE/6THLE。结果治疗组在涂片及培养阴转率均高于对照组,差异有统计学意义(P<0.05);治疗组在3、6、9个月时,病变吸收率明显优于对照组,差异有统计学意义(P<0.05);2组患者的不良反应无明显差异(P>0.05)。结论左氧氟沙星联合卷曲霉素治疗耐多药结核病,疗效满意。
Objective To observe the therapeutic effects in the treatment of MDR-TB with levofloxacim and Capreo- mycin. Methods 124 cases were divided into two groups in a randomized way; the treatment group （n = 62 ） and the control group（ n =62）. The treatment were 3VCLTHZ/6CVL and 3LKZTHE/6THLE for the treatment group and control group,respectively. Results The treatment group and raises the cloudy rate of rotation in the smear to be higher than the control group,2 groups of comparison differences have statistics significance（P 〈 0.05 ） ;Treatment group when 3,6,9months, the pathological change absorption rate surpasses the control group obviously, the difference has statistics significance （P 〈 0.05 ） ;2 group of patient＇s untoward effect not obvious differences （ P 〉 0. 05）. Conclusion Significant results were achieved when choosing levofloxacin and capreomycin for treating MDR-TB.
出处
《临床合理用药杂志》
2009年第16期25-26,共2页
Chinese Journal of Clinical Rational Drug Use
