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老年慢性肾脏病的临床流行病学研究 被引量:4

Clinical epidemiological study of elderly chronic kidney diseases
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摘要 目的调查肾内科门诊老年慢性肾脏病(CKD)患者的基础状况,判断老年CKD患者肾功能下降的危险因素。方法对中山大学附属第三医院肾内科门诊就诊的老年慢性肾脏病患者进行为期9个月的前瞻性横断面调查。结果共有141例病例入选。前五位老年慢性肾脏病的病因分别为原发性肾小球疾病41例(29.0%),高血压肾病41例(29.0%),糖尿病肾病23例(16.3%),尿酸性肾病10例(7.1%),良性肾小动脉硬化9例(6.4%)。病例平均年龄70.3岁。CKD各期的分布为CKD1期17.0%、CKD2期21.3%、CKD3期24.8%、CKD4期15.6%、CKD5期21.3%。多因素回归提示年龄、蛋白尿与肾功能下降独立相关。结论该研究针对老年CKD患者进行大规模单中心横断面调查,将有助于确定老年CKD患者的基本状况,为进一步纵向随访奠定基础。 Objective To present the baseline characteristics of elderly chronic kidney diseases (CKD) in a single center. Methods A cross-sectional study was carried out. Results A total of 141 patients were enrolled in a period of 9 months. The top five causes of CKD in these patients were primary glomerular disease, essential hypertension, diabetic nephropathy, uric acid nephropathy and benign nephrosclerosis. The mean age of the patients was 70.3 years old. The distribution of CKD stage was CKD1 stage being 17.1%, CKD2 stage 21.3 %, CKD3 stage 24.8%, CKD4 stage 15.6% and CKD5 stage 21.3%. The age and proteinuria were independently correlated with the reduced renal function. Conclusions This large cross-sectional study will help to perform a prospective cohort study in elderly Chinese CKD patients.
出处 《中国校医》 2009年第4期385-386,共2页 Chinese Journal of School Doctor
关键词 肾疾病 老年人 肾小球滤过率 横断面研究 Kidney Disease Elderly Glomerular Filtration Rate Cross-Sectional Study
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