新型杀螨剂丁氟螨酯的合成研究

Synthesis of Acaricide Cyflumetofen

以对叔丁基苯乙腈为原料,与碳酸二甲酯反应得到2-(4-叔丁基苯基)-2-氰基乙酸乙酯,再进行酯交换反应,最后与邻三氟甲基苯甲酰氯缩合制得丁氟螨酯,含量≥96%,总收率为46.8%(以对叔丁基苯乙腈计)。

Acaricide cyflumetofen was synthesized with the starting material p-tert-butylphenylacetonitrile by three steps of reaction, its total yield was 46.8% （calculated by p-tert-butylphenylacetonitrile）, the content≥96%.