瑞芬太尼与芬太尼复合异丙酚麻醉用于胃镜检查术的临床观察

CLINICAL INVESTIGATION OF PROPOFOL ANESTHESIA COMBINED WITH FENTANYL OR REMIFENTANYL FOR GASTROSCOPY

目的:比较三种不同静脉麻醉方法行胃镜检查术的麻醉效果。方法:将择期行胃镜检查术患者120例,随机分为异丙酚组(P组)、芬太尼复合异丙酚组(F组)、瑞芬太尼复合异丙酚组(R组),每组40例。P组单纯静注异丙酚2.5mg/kg;F组先后静注芬太尼1.0μg/kg、异丙酚1.5mg/kg;R组先后静注瑞芬太尼0.5μg/kg、异丙酚1.5mg/kg。患者入睡后开始手术。术中如有影响手术操作的体动和呛咳,追加异丙酚0.5mg/kg。结果:与P组比较,F组和R组麻醉效果满意,异丙酚用量明显减少(P<0.05),术毕清醒及离院时间更短(P<0.05)。结论:芬太尼及瑞芬太尼复合异丙酚均可有效而安全的用于胃镜检查术。

Objective：To observe the anesthetic effect of 3 different intravenous anesthesia for gastroseopy. Methods： 120 patients were randomly divided into propofol group（ P group）, fentanyl propofol group（ F group） and remifentanil propofol group （ R group）,40 patients in each group. Propofol 2.5mg/kg, Fentanyl 1μg/kg＋Propofol 1.5mg/kg, Remifentanyl 0.5μg/kg＋Propofol 1.5mg/kg were injected intravenously in P group, F group and R group respectively. Gastroscopy started when patient was sedated. 0.5mg/kg propofol was added whenever patient was moving or coughing. Results：Compared with P group, better anesthetic effect was obtained in F and R groups. The dosage of propofol was obviously decreased （ P〈 0.05） and the time of revival and hospitalization was shorter in F and R groups （P〈 0.05）.Conclusion： Propofol anesthesia combined with fentanyl or remifentanil is safe for gastroscopic examination.