D-二聚体定量检测对判定急性冠脉综合征血栓形成的研究

Significance of test D-dimer in judging the thrombosis of coronary artery in acute coronary syndrome

目的:探讨D-二聚体定量检测对于判定急性冠脉综合征(ACS)血栓形成的意义。方法:选择住院不稳定型心绞痛(UAP)患者36例,急性心肌梗塞(AMI)患者13例,稳定型心绞痛(SAP)患者23例,采用胶体金标法动态检测患者静脉血中的D-二聚体含量。结果:D-二聚体含量:UAP组(0.95±0.32)mg/L,AMI组(1.82±0.63)mg/L,UAP组与SAP组(0.39±0.15)mg/L比较有显著差异(P<0.05),AMI组与SAP组比较,差异非常显著(P<0.01)。结论:D-二聚体定量检测是判定ACS血栓形成相对特异的敏感指标。

Objective： To study the clinical significance of D-dimer judging the thrombosis of coronary artery in acute coronary syndrome （ACS） patients. Methods： The 36 hospitalized patients with unstable angina pectoris （UAP） regard as UAP group, 13 patients with acute myocardial infarction （AMI） as AMI group, 23 patients with stable angina pectoris （SAP） as SAP group. The D dimer in their venous blood were estimated by ELISA methods. Results： D- dimer cotent was （0.95±0.32） mg/Lin UAP group, was （1.82±0.63） mg/L in AMI group, was （0.39±0.15） mg/L in SAP group. The difference was significant among SAP and UAP group （P〈0.05）, AMI group （P〈0. 01）. Conclusion： Test the content of D-dimer is a comparative distinctive, sensitive marker in judgement thrombosis of coronary artery.