巯基乙酸对蟾蜍血清转氨酶和钙含量的影响

Effect of Thioglycolic Acid on AST,ALT and Ca^(2+) of Serum in Bufo gargarizans

以健康的中华蟾蜍为实验动物,研究皮肤染毒巯基乙酸(TGA)对血液天门冬氨酸氨基转氨酶(AST)、丙氨酸氨基转氨酶(ALT)和钙含量的影响,并对其作用机理进行初步探讨。试验结果表明,染毒巯基乙酸剂量对于血清AST、ALT和Ca含量影响效果明显。方差分析表明各试验处理组与对照组相比差异显著;染毒TGA的时间对于血清生化指标的影响呈现累积趋势,各试验处理组染毒后期与前期差异显著。表明巯基乙酸对于蟾蜍肝组织等器官具有明显的损伤作用,因此化工产品巯基乙酸对水体的污染不容忽视。

The influence of thioglycolic acid on healthy Bufo gargarizans was studied. The results are as follows： The effect of exposed doses to aspartate aminotransferase （ AST）, alanine aminotransferase （ALT） and Ca2＋ in the serum was significant. The analysis of variance test showed that there was a significant difference between the treatment group and the control group; the effect of exposure time to the serum biochemical indicators had a cumulative trend. Analysis of variance showed that there was a significant difference between pre-exposure and lat-exposure. Thioglyeolie acid has obvious toxicity to tile liver of Bufo gargarizans. The pollution of thiogiyeolie acid to water can＇t be ignored.