高血压及其合并糖尿病患者的心脏变时性临床分析

Analysis of the Chronotropic Response Change in Patients with Essential Hypertension(EH) and Essential Hypertension Complicated with Diabetes Mellitus(DM)

目的:探讨原发性高血压(EH)及其合并糖尿病患者(DM)的心脏变时性功能的变化。方法:选择50例高血压患者、40例高血压合并糖尿病患者以及50例体检者。所有患者均完成活动平板运动实验并测定心率变时性反应指数(CRI2)。结果:高血压组、高血压合并糖尿病组的CI较对照组均显著升高,P<0.05,有统计学意义,且高血压合并糖尿病组的CI较高血压组显著升高,P<0.05,有统计学意义。结论:高血压、高血压合并糖尿病患者均有不同程度的自主神经功能的损伤,心脏的变时性功能变化可反映心脏的自主神经功能变化。

Objective To explore the change of cardiac ehronotropie in patients with essential hypertension（EH） and EH complicated with diabetes mellitus（DM）. Methods Study included 50 cases of EH, 40 cases of EH complicated with DM and 50 healthy people. Every case completed exercise treadmill tests and was detected the index of heart rate chronotropic response （CI）. Results CI of EH group and EH complicated with DM group was significantly higher than that of control group （ P 〈 0.05）, and CI of EH complicated with DM group was markedly higher than that of EH group （ P 〈 0.05）. Conclusions The patients with EH and EH complicated with DM had different degree of damnification of autonomic nerve activity, heart rate chronotropic response could reflect the fimction of autonomic nerve.