2007年我院细菌流行分布及耐药情况分析

Analysis on distribution of germ population and drug resistance in the hosipital in 2007

目的了解医院细菌流行分布及耐药性变化趋势。方法采用湖南天地人微生物分析仪,酵母样真菌用科马嘉显色培养基,流感嗜血杆菌和卡他莫拉氏菌药敏用纸片扩散(K-B)法。结果2007年度标本的主要来源为呼吸道标本以革兰阴性菌以及酵母样真菌感染为主。其耐药性以非发酵菌中的嗜麦芽单胞菌最高,其次为肠杆菌科的阴沟肠杆菌。革兰阳性菌中金黄色葡萄球菌的感染呈下降趋势,其耐药率也呈下降趋势;凝固酶阴性的葡萄球菌的感染有上升趋势。结论临床应该注意根据微生物实验室所提供的细菌流行分布及耐药情况分析合理使用抗生素,避免不必要使用抗菌药物。同时应该提高对血培养的认识程度,充分利用血培养药敏结果。

Objective To realize the distribution of bacilli and the tendency of their drug resistance in hospital. Methods Hunan Tiandiren microbial analytic apparatus was applied for this study, yeast - like fungi were cultured in special culture medium, and examination of antibiotic susceptibility testing of Haemophilus influenza and Moraxella catarrhalis in respiratory infections was carried out by application of K - B method. Results The main source of samples was from respiratory tract and the pathogens were mainly consists of Gram - negative bacteria and yeast - like fungi in 2007. The dnig resistance was highly involved in Stenotrophomonas maltophilia, secondly it is involved in Enterobacter cloacae. The infection trend of Staphylococcus aureus in Gram - positive bacteria is dropped down as well as its rate of drug resistance will drop down as well, and the infection trend of coagulase - negative Staphylococci （CNS） is increased. Conclusion It should be noted that according to results of clinical microbiological laboratory on analysis of distribution and prevalence of drug -resistant bacteria, the rational use of antibiotics is important. The unnecessary use of antimicrobial agents should be avoided. At the same time, awareness of application of blood culture should be raised and the extent of making full use of these results about drug sensitivity in clinical practice is also very important.